Chrysalis Intelligence · Sponsors · Roche Diagnostics Operations

Roche Diagnostics Operations

Indianapolis, IN, US · 2 510(k) clearances · 6 PMAs · 28 recalls

Total clearances
2
2024-02-20 → 2025-01-24
Last 12 months
0
Product codes
2
Most recent
2025-01-24
Trend

Clearance cadence by quarter

Portfolio

Product codes worked

Code Device name Class Specialty Clearances Most recent
DFC 1 2025-01-24
LAO Enzyme Immunoassay, Methotrexate Unclassified Unknown 1 2024-02-20
Class III

PMA approvals (6)

Total PMA records
6
Originals + supplements
Distinct product codes
2
First decision
2023-04-18
Most recent
2025-05-22
DatePMA #Trade nameTypeCodeDevice nameSpecialty
2025-05-22 P130015-S022 Elecsys HBeAg 30-Day Notice LOM Test, Hepatitis B (B Antigen, B Surface Antigen, Be Antigen) Microbiology
2024-10-03 P130015-S021 Elecsys HBeAg 30-Day Notice LOM Test, Hepatitis B (B Antigen, B Surface Antigen, Be Antigen) Microbiology
2024-08-29 P130015-S020 Elecsys HBeAg 30-Day Notice LOM Test, Hepatitis B (B Antigen, B Surface Antigen, Be Antigen) Microbiology
2024-02-08 P130015-S019 Elecsys HBeAg 30-Day Notice LOM Test, Hepatitis B (B Antigen, B Surface Antigen, Be Antigen) Microbiology
2023-10-31 P130015-S018 Elecsys HBeAg 30-Day Notice LOM Test, Hepatitis B (B Antigen, B Surface Antigen, Be Antigen) Microbiology
2023-04-18 P130015-S017 Elecsys HBeAg Test System Normal 180 Day Track
Safety

Recalls (28)

Class I (serious)
0
Risk of injury / death
Total recalls
28
Currently ongoing
14
Most recent
2026-01-20
DateSeverityStatusRecall # ProductCodeReason
2026-01-20 Class II Ongoing Z-1476-2026 cobas pro integrated solutions with cobas c 503 analytical units: cobas pro sample supply unit, material number 08464… Software defect, which allows the system to accept erroneous, non-monotonous calibrations for Spline-type assays. Cobas pro integrated solutions is an automated…
2025-11-21 Class II Ongoing Z-1009-2026 The Elecsys Anti-TSHR immunoassay is a three-step competitive immunoassay with streptavidin-coated microparticles and el… Issues identified: 1) Results vary by Instrument Platform; 2) Calibrator Lot-to-Lot Variability. Issues may lead to delayed or incorrect diagnosis, as well as d…
2024-10-17 Class II Ongoing Z-0489-2025 cobas HCYS, Homocysteine Enzymatic Assay, Material Number REF 06542921190, for use on cobas c 701/702, in vitro test for… Abnormal calibration signals and control recovery issues on the Homocysteine Enzymatic (HCYS) Assay can produce erroneous patient results (positive or negative …
2024-08-15 Class II Ongoing Z-3187-2024 Creatine Kinase (CK) used on cobas c 311/501/502 and COBAS INTEGRA 400 plus-In vitro test for the quantitative determina… Creatine Kinase (CK) Assay Abnormal calibrations on the cobas¿ c 311/501/502 and COBAS INTEGRA 400 plus Analyzers may lead to erroneous results and misdiagnosis…
2023-10-03 Class II Ongoing Z-0352-2024 Tina-quant D-Dimer Test System, Fibrinogen/Fibrin Degradation Products Assay, Material Numbers 03001245322 - (cobas c 31… Elevated results were detected with Li-heparin plasma samples when compared to citrated plasma samples.
2022-12-12 Class II Ongoing Z-0952-2023 cobas infinity central lab, Material Number 07154003001 A complaint investigation revealed that an incorrect behavior relating to the rejection of orders capability of the Host Connectivity Agent (HCA) could occur wh…
2022-07-14 Class II Ongoing Z-1515-2022 cobas e801 Immunoassay Analyzer Software issue resulting in signals and sample test results of Pre-Wash tests being impacted. The following assays are considered impacted by the issue: Anti-HA…
2021-10-18 Class II Terminated Z-0266-2022 Cobas u 601 urinalysis test system, Catalog number 06334601001 The cobas U 601 urinalysis test system is comprised of t… A potential risk for false negative nitrite results exists when endogenous creatinine levels are 15,000 mg/L and above. No interference of Nitrite results was o…
2021-06-24 Class II Terminated Z-2444-2021 cobas infinity central lab running software version 3.01.03 through 3.02.08, Catalog#: 07154003001 Under specific circumstances created by the user, the cobas e flow test results could be replaced by an automatic result sent to the lab LIS. This automatic res…
2021-04-26 Class II Ongoing Z-1675-2021 IRON GEN 2: ROCHE COBAS INTEGRA ANALYZER, REAGENT CASSETTES, Catalog#: 03183696122 - Product Usage: In vitro test for th… Roche received several complaints regarding increased control recovery and discrepant elevated results for the Iron Gen.2 (IRON2) assay on the cobas c311, 501, …
2021-04-07 Class II Ongoing Z-1596-2021 Elecsys Troponin I Immunoassay: Catalog# 05094810160 - Product Usage: intended to aid in the diagnosis of myocardial inf… Recall reason is possible sporadic false negative conventional troponin results. Roche has confirmed an issue with running Elecsys Troponin I/Troponin I STAT an…
2021-04-07 Class II Ongoing Z-1595-2021 Elecsys Troponin I STAT Immunoassay: Catalog# 05094798160 - Product Usage: intended to aid in the diagnosis of myocardia… Recall reason is possible sporadic false negative conventional troponin results. Roche has confirmed an issue with running Elecsys Troponin I/Troponin I STAT an…
2021-01-06 Class II Terminated Z-1098-2021 9180 Electrolyte Analyzer - Product Usage: intended to be used for the measurement of sodium, potassium, chloride, ioniz… May display Calcium results on the screen with wrong arrow direction which may lead to misinterpretation of results and incorrect medical decision. If the unit …
2020-12-17 Class II Terminated Z-0883-2021 A calculator/data processing module for clinical use is an electronic device intended to store, retrieve, and process la… A software error results in the unintentional removal of the serum-indices flag that would otherwise prevent the release of results. The Cobas Inifinity has an …
2020-12-08 Class II Ongoing Z-0755-2021 Roche cobas pro integrated solutions (cobas pro ISE, cobas c 503, and cobas e 801 analytical units) Chemistry Analyzer (… Potential for Changed Configuration Settings on the cobas 8000 modular analyzer series/cobas pro integrated solutions, may cause incorrect results in several af…
2020-12-08 Class II Ongoing Z-0754-2021 Roche cobas 8000 modular analyzer series (i.e., cobas 8000 ISE module; cobas c 502, 701, and 702 modules; and cobas e 60… Potential for Changed Configuration Settings on the cobas 8000 modular analyzer series/cobas pro integrated solutions, may cause incorrect results in several af…
2020-12-02 Class II Terminated Z-0804-2021 CoaguChek XS PST Meters- IVD (Patient Self-Testing) measures blood-clotting time for people who are taking anticoagulati… Possible Misinterpretation of Displayed Measuring Units from INR to %Quick or Seconds; providing instructions to users for ensuring the meter is displaying INR…
2020-12-02 Class II Terminated Z-0803-2021 CoaguChek XS Prof (Professional) Meters- IVD professional healthcare providers for quantitative prothrombin time testing… Possible Misinterpretation of Displayed Measuring Units from INR to %Quick or Seconds; providing instructions to users for ensuring the meter is displaying INR…
2020-11-23 Class II Terminated Z-0752-2021 cobas pro integrated solutions -cobas c 503, Analyzer, chemistry (photometric discrete), for clinical use During the subsequent pipetting (1st or 2nd measurement), the residual reagent can sporadically be transferred from the conus into the reaction cuvette and lea…
2020-11-06 Class II Terminated Z-0634-2021 Tina-quant C-Reactive Protein Gen.3, Catalog number 05172373190 - Product Usage: the in vitro quantitative determination… Roche confirmed customer complaints of low quality (QC) recovery and invalid calibrations for the Tina-quant C-Reactive Protein Gen. 3 on the cobas c701 and 702…
2020-10-09 Class II Terminated Z-0461-2021 cobas infinity central lab/cobas infinity core license-The cobas infinity IT solutions application is intended to be use… Potential Incorrect Validation of Results Due to an Erroneous QC Status When Using Status Expiration Control Rule
2020-08-31 Class II Ongoing Z-0086-2021 DISCOVERY ULTRA Advanced Staining System (RUO-Research Use Only) Material Number: 05987750001 Potential for Fluid leaks within the instruments, creating an electrical short inside the power socket, which generates heat, smoke, and eventually burning and …
2020-08-31 Class II Ongoing Z-0085-2021 BenchMark ULTRA Advanced Staining System (IVD)- Material Number: 05342716001 Potential for Fluid leaks within the instruments, creating an electrical short inside the power socket, which generates heat, smoke, and eventually burning and …
2020-08-27 Class III Terminated Z-0104-2021 Albumin Gen.2, Catalog 05166861190 Roche has confirmed customer complaints of low quality (QC) recovery and invalid calibrations for the identified products. A discoloration (yellow color) was ob…
2020-08-27 Class III Terminated Z-0103-2021 Tina-quant Complement C4 ver.2, Catalog 05991994190 Roche has confirmed customer complaints of low quality (QC) recovery and invalid calibrations for the identified products. A discoloration (yellow color) was ob…
2020-08-20 Class II Terminated Z-2981-2020 Elecsys Anti-TPO Assay on cobas e analyzers 411, 601, 602, Catalog Number 06368590190 Recent internal verification studies found the current RF interference claim to no longer be met for the assay on the cobas e 411, 601, and 602 analyzers. There…
2020-02-07 Class II Terminated Z-1444-2020 Elecsys CA 19-9, Cat. No. 07027028190 - Product Usage: the product is an immunoassay for monitoring and management of pa… The firm has received an increased number of complaints concerning non-reproducible elevated results ("high flyers") for one lot of Elecsys CA 19-9 reagent, whi…
2020-01-07 Class II Terminated Z-1158-2020 cobas infinity core, Material No. 7154003001. The device is a calculator/data processing module, for clinical use. Alarm flags that have a "<" symbol in front of them are not displayed on the cobas infinity Validation screen. This issue affects only customers that are doing …
Filings

All 510(k) clearances (2)

Date K-number Device Code Class Specialty
2025-01-24 K241220 Tina-quant Lipoprotein(a) Gen.2 Molarity DFC
2024-02-20 K233454 ONLINE TDM Methotrexate LAO Unclassified Unknown