Chrysalis Intelligence · Sponsors · Hologic, Inc.

Hologic, Inc.

San Diego, CA, US · 25 510(k) clearances · 55 PMAs · 25 recalls (2 Class I)

Total clearances
25
2020-03-23 → 2026-08-12
Last 12 months
4
Product codes
17
Most recent
2026-08-12
Name variants in FDA filings: Hologic, Inc. / Hologic
Trend

Clearance cadence by quarter

Portfolio

Product codes worked

Code Device name Class Specialty Clearances Most recent
QDQ Radiological Computer Assisted Detection/Diagnosis Software For Lesions Suspicious For Cancer Class II Radiology 4 2025-07-31
QOF Multi-Target Respiratory Specimen Nucleic Acid Test Including Sars-Cov-2 And Other Microbial Agents Class II Microbiology 3 2024-11-15
QEP 3 2022-06-03
PCH Gastrointestinal Pathogen Panel Multiplex Nucleic Acid-Based Assay System Class II Microbiology 2 2025-09-25
KNW Instrument, Biopsy Class II Gastroenterology, Urology 1 2026-08-12
GEI Electrosurgical, Cutting & Coagulation & Accessories Class II General, Plastic Surgery 1 2026-06-17
QQX Respiratory Specimen Nucleic Acid Sars-Cov-2 Test Class II Microbiology 1 2025-02-13
PAB Cytomegalovirus (Cmv) Dna Quantitative Assay Class II Microbiology 1 2025-01-17
PQA 1 2024-11-25
HIG Insufflator, Hysteroscopic Class II Obstetrics/Gynecology 1 2024-07-25
MZP 1 2024-07-24
QYV 1 2024-01-31
LSL 1 2024-01-26
MKZ Dna Probe, Nucleic Acid Amplification, Chlamydia Class I Microbiology 1 2023-11-16
OUY Trichomonas Vaginalis Nucleic Acid Amplification Test System Class II Immunology 1 2023-11-06
OCC Respiratory Virus Panel Nucleic Acid Assay System Class II Microbiology 1 2023-05-05
IZH System, X-Ray, Mammographic Class II Radiology 1 2020-10-05
Class III

PMA approvals (55)

Total PMA records
55
Originals + supplements
Distinct product codes
7
First decision
2020-01-21
Most recent
2026-03-05
DatePMA #Trade nameTypeCodeDevice nameSpecialty
2026-03-05 P920048-S029 Rapid fFN for the TLiIQ System 30-Day Notice LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2026-03-05 P920048-S028 Rapid fFN for the TLiIQ System 30-Day Notice LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2025-12-17 P010013-S094 NovaSure Model 10 RF Controller 30-Day Notice MNB
2025-11-24 P080003-S011 Envision Mammography Platform Normal 180 Day Track No User Fee OTE Digital Breast Tomosynthesis Unknown
2025-10-07 P170025-S023 Aptima HBV Quant Assay Kit, 100T; Aptima HBV Quant Calibrator Kit; Aptima HBV Quant Controls Kit; Aptima HBV Quant Targe 30-Day Notice MKT Hepatitis Viral B Dna Detection Microbiology
2025-08-27 P950039-S041 ThinPrep Processor and ThinPrep Imaging System 30-Day Notice MKQ Processor, Cervical Cytology Slide, Automated Unknown
2024-12-06 P920048-S027 Rapid fFN Cassette Kit for the TLiIQ System, Rapid fFN Control for the TLiIQ System 30-Day Notice LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2024-10-23 P920048-S026 TLiIQ QCette 30-Day Notice LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2024-10-23 P210029-S002 Aptima CMV Quant Assay 30-Day Notice PAB Cytomegalovirus (Cmv) Dna Quantitative Assay Microbiology
2024-10-23 P170025-S022 Aptima HBV Quant Assay 30-Day Notice MKT Hepatitis Viral B Dna Detection Microbiology
2024-09-06 P010013-S093 NovaSure Impedance Controlled Endometrial Ablation System 30-Day Notice MNB
2024-07-23 P010013-S092 NovaSure Impedance Controlled Endometrial Ablation System 30-Day Notice MNB
2024-07-05 P080003-S009 Envision Mammography Platform Normal 180 Day Track OTE Digital Breast Tomosynthesis Unknown
2024-06-17 P170025-S019 Aptima HBV Quant Assay Normal 180 Day Track MKT Hepatitis Viral B Dna Detection Microbiology
2024-05-29 P080003-S010 Selenia Dimensions/3Dimensions Normal 180 Day Track No User Fee OTE Digital Breast Tomosynthesis Unknown
2024-05-08 P170025-S021 Aptima HBV Quant Assay 30-Day Notice MKT Hepatitis Viral B Dna Detection Microbiology
2023-12-21 P920048-S025 Rapid fFN for the TLiIQ System 30-Day Notice LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2023-11-24 P170025-S020 Aptima HBV Quant Assay 30-Day Notice MKT Hepatitis Viral B Dna Detection Microbiology
2023-10-27 P010013-S091 NovaSure Impedance Controlled Endometrial Ablation System 30-Day Notice MNB
2023-09-22 P010013-S090 NovaSure Impedance Controlled Endometrial Ablation System 30-Day Notice MNB
2023-08-24 P920048-S024 Rapid fFN for the TLilQ System Special (Immediate Track) LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2022-12-01 P010013-S089 NovaSure Impedance Controlled Endometrial Ablation System Special (Immediate Track) MNB
2022-11-02 P010013-S088 NovaSure Impedance Controlled Endometrial Ablation System 30-Day Notice MNB
2022-08-04 P010013-S087 NovaSure Impedance Controlled Endometrial Ablation System 30-Day Notice MNB
2022-07-20 P210029-S001 Aptima CMV Quant Assay 30-Day Notice PAB Cytomegalovirus (Cmv) Dna Quantitative Assay Microbiology
2022-07-20 P170025-S018 Aptima HBV Quant Assay 30-Day Notice MKT Hepatitis Viral B Dna Detection Microbiology
2022-05-09 P920048-S023 Rapid fFN for the TLiIQ System 30-Day Notice LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2022-05-09 P210029 Aptima CMV Quant Assay Original PAB Cytomegalovirus (Cmv) Dna Quantitative Assay Microbiology
2022-04-13 P920048-S022 Rapid fFN for the TLiIQ System 30-Day Notice LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2022-02-28 P920048-S021 Rapid fFN for the TLiIQ System 30-Day Notice LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2022-02-25 P170025-S017 Aptima HBV Quant Assay Real-Time Process MKT Hepatitis Viral B Dna Detection Microbiology
2022-01-04 P010013-S085 NovaSure Impedance Controlled Endometrial Ablation System Normal 180 Day Track No User Fee MNB
2021-12-09 P010013-S082 NovaSure Impedance Controlled Endometrial Ablation System Normal 180 Day Track MNB
2021-11-15 P010013-S086 NovaSure Impedance Controlled Endometrial Ablation System 30-Day Notice MNB
2021-08-30 P010013-S084 NOVASURE IMPEDANCE CONTROLLED ENDOMETRIAL ABLATION SYSTEM 30-Day Notice MNB
2021-06-30 P010013-S081 NovaSure Impedance Controlled Endometrial Ablation System Normal 180 Day Track MNB
2021-05-21 P920048-S019 Rapid fFN for the TLiIQ System Normal 180 Day Track No User Fee LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2021-05-14 P950039-S040 ThinPrep Genesis Processor Normal 180 Day Track MKQ Processor, Cervical Cytology Slide, Automated Unknown
2021-04-29 P920048-S020 Rapid fFN for the TLilQ System 30-Day Notice LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2021-03-30 P010013-S083 NovaSure Impedance Controlled Endometrial Ablation System 30-Day Notice MNB
2020-11-06 P920048-S015 Rapid fFN for the TLiIQ System 135 Review Track For 30-Day Notice LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2020-10-27 P010013-S080 NovaSure Impedance Controlled Endometrial Ablation System 30-Day Notice MNB
2020-10-19 P010013-S079 NovaSure Impedance Controlled Endometrial Ablation System 30-Day Notice MNB
2020-10-02 P920048-S018 Rapid fFN for the TLiIQ System 30-Day Notice LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2020-09-03 P920048-S016 Rapid fFN for the TLiIQ System Real-Time Process LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2020-08-12 P950039-S039 ThinPrep Processors and ThinPrep Imaging System 135 Review Track For 30-Day Notice MKQ Processor, Cervical Cytology Slide, Automated Unknown
2020-08-12 P920048-S017 Rapid fFN for the TLiIQ System 30-Day Notice LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2020-07-21 P170025-S016 Aptima HBV Quant Assay 30-Day Notice MKT Hepatitis Viral B Dna Detection Microbiology
2020-07-21 P160023-S019 Aptima HCV Quant Dx Assay 30-Day Notice MZP
2020-03-02 P010013-S075 NovaSure Impedance Controlled Endometrial Ablation System Real-Time Process MNB
2020-02-14 P170025-S015 Aptima HBV Quant Assay 30-Day Notice MKT Hepatitis Viral B Dna Detection Microbiology
2020-02-14 P160023-S017 Aptima HCV Quant Dx Assay 30-Day Notice MZP
2020-01-28 P920048-S013 Rapid fFN for the TLiIQ System, Fetal Fibronectin Enzyme Immunoassay Normal 180 Day Track LKV Enzyme Immunoassay, Fetal Fibronectin Unknown
2020-01-21 P170025-S014 Aptima HBV Quant Assay Real-Time Process MKT Hepatitis Viral B Dna Detection Microbiology
2020-01-21 P160023-S016 Aptima HCV Quant Dx Assay Real-Time Process MZP
Safety

Recalls (25)

Class I (serious)
2
Risk of injury / death
Total recalls
25
Currently ongoing
22
Most recent
2026-04-08
DateSeverityStatusRecall # ProductCodeReason
2026-04-08 Class II Ongoing Z-2168-2026 3DIMENSIONS MAMMOGRAPHY SYSTEM; Model Numbers: 3DM-SYS-INTL2D, 3DM-SYS-INTL2D-MOB, 3DM-SYS-INTL2D-NS, 3DM-SYS-INTL3D, 3D… Complaints have been received of systems developing loose, missing, or broken internal bolts over time.
2026-04-08 Class II Ongoing Z-2167-2026 SELENIA DIMENSIONS MAMMOGRAPHY SYSTEMS. Model Numbers: SDA-SYS-3000-2D-HTC, SDA-SYS-3000-3D, SDM-SYS-6000-2D, SDM-SYS-60… Complaints have been received of systems developing loose, missing, or broken internal bolts over time.
2026-03-23 Class II Ongoing Z-1949-2026 Brand Name: Genius" Review Station Product Name: Genius" Review Station Display (Barco Monitor) Model/Catalog Number: … It was identified that certain devices were being operated outside the validated and FDA-cleared display configuration due to user modification of the manufactu…
2026-02-18 Class II Ongoing Z-1586-2026 Brand Name: Aptima HPV Assay Product Name: Aptima HPV Assay Model/Catalog Number: 303585 Product Description: Aptima … Due to product exhibiting potential to generate either invalid or false negative results.
2025-12-15 Class II Ongoing Z-1314-2026 Brevera Breast Biopsy System Disposable 9 Gauge Needle. Biopsy Instrument. Presence of particulates in affected devices that can be deposited into breast tissue during use.
2025-12-12 Class II Ongoing Z-1093-2026 ThinPrep¿ CytoLyt¿ Solution. Buffered Cell Wash Solution. Fungal contamination of affected lot with Parengyodontium album.
2025-01-15 Class II Ongoing Z-1170-2025 Brand Name: Sertera Biopsy Device Product Name: Sertera Biopsy Device Model/Catalog Number: Sertera-14 Software Versi… Devices presented a condition in which the inner needle separated from the hub and produced a longer throw of the inner needle or dislodgement.
2025-01-08 Class II Ongoing Z-1095-2025 The Rapid fFN Specimen Collection Tube (PN: 71550-001) is a component of the Rapid fFN Specimen Collection kit (PN: 7173… Three lots of Rapid fFN Specimen Collection kit (901164, 901165, and 904850) contain Rapid fFN Specimen Collection Tubes which may be empty, underfilled, or ove…
2024-12-13 Class II Ongoing Z-0907-2025 Panther Fusion GBS Assay REF PRD-04484 Kit containing Panther Fusion GBS Reagent Cartridge IVD. Potential weak pouch seal on Panther Fusion GBS assay cartridge, causing potential for invalid or incorrect results leading to a possible delay of treatment.
2024-11-08 Class II Ongoing Z-0694-2025 Panther Fusion SARS-CoV-2/Flu A/B/RSV Assay, REF: PRD-07400 SARS-CoV-2/Flu A/B/RSV Assay Kit may erroneously produce SARS-CoV-2 false positive results.
2024-10-10 Class I Ongoing Z-0328-2025 BioZorb Marker. Radiographic soft tissue marker. Firm received reports of adverse events/complications that include serious injuries, such as pain, infection, rash, device migration, device erosion, seroma, an…
2024-08-19 Class II Ongoing Z-3248-2024 Selenia Dimensions/ 3Dimensions-Digital breast tomosynthesis Software Version Dimensions 1.12.0 and 3Dimensions 2.3.0 s… Identified an issue with Selenia Dimensions 1.12.0 and 3Dimensions 2.3.0 system software when used in combination with C-View software in which the quality of t…
2024-06-13 Class II Ongoing Z-2373-2024 Horizon X-Ray Bone Densitometer (DXA) Models: Horizon-A, Horizon-W, Horizon-WI, Horizon-C, Horizon-CI, Horizon-A-CN, … Non-conformance pertains to electromagnetic compatibility requirements according to the international technical standard IEC 60601-1-2 for the safety and essent…
2024-03-13 Class I Ongoing Z-1733-2024 BioZorb Marker-BioZorb 3D Bioabsorbable Marker-Intended Use radiographic marking of sites in soft tissue. 1) F0405 BioZ… Safety Information: Complaints describe complications/adverse events that include pain, infection, rash, device migration, device erosion, seroma, discomfort, o…
2023-12-15 Class II Ongoing Z-0782-2024 PANTHER FUSION System REF 9121010000 The Panther System is an integrated nucleic acid testing system which fully au… Due to potential false positive Flu B results when a sample was also SARS-CoV-2 positive.
2023-09-14 Class II Ongoing Z-1371-2024 Aptima CMV Quant Assay, Reference numbers: AW-22600-001, AW-25509-001, and AW-26381-001 Amplification Reagent, Enzyme Re… Use of assay along with plasma specimen may result in error code which would invalidate sample.
2023-05-02 Class II Ongoing Z-2035-2023 Sertera 14 Gauge Biopsy Device-intended to obtain percutaneous core biopsy samples from soft tissue and tumors of the br… The inner needle of the Sertera device is either detaching or discharging and may cause delay in surgery
2023-01-16 Class II Ongoing Z-1144-2023 Hologic 3Dimensions/Selenia Dimensions Models: RM-SDM-00001-3D SDM-00001-2D SDM-00001-3D SDM-05000-3D3 SDM-05000-… C-Arm unexpected movement may cause blunt trauma should the tube arm impinge upon an individual
2022-10-10 Class II Completed Z-0669-2025 Hologic Sizer Set- sterilization tray and 6 individual sizers, intended as a Surgical instrument guide Model/Catalog Nu… IFU was not provided with the Sizer Set sterilization tray Revised Sterilization Instructions for Sizer Set
2022-08-09 Class II Ongoing Z-1858-2022 The BioZorb LP Marker is an implantable radiopaque marker used to facilitate visualization of a soft tissue site. The Bi… Hologic BioZorb LP Marker, (Product number F0221), lot number 22A0RL, contained removable labels with an expiration date that indicated the product had already …
2022-03-18 Class II Ongoing Z-0877-2022 Panther Fusion GBS Assay Cartridges 96 Tests, Catalog Number: PRD-04484. in vitro diagnostic test for group b streptoco… Samples, run on a GBS Assay, that have analyte concentrations that are at or near the limit of detection may produce false negative results.
2022-01-27 Class II Ongoing Z-0750-2022 Panther Fusion Extraction Reagent-X, REF PRD-04477, For use with Panther Fusion System, IVD, Rx only, Contents: FCR-X Fu… Failed stability specifications for reagent kits that may result in false negative test results.
2021-02-26 Class II Ongoing Z-1369-2021 Panther Fusion Tube Tray, REF PRD-04000, PN: FA-15004, Cont. 18 Tube Trays - Product Usage: an ancillary consumable to t… There is a potential for tube trays to leak which could potentially result in false positive results, false negative results or invalid patient results.
2020-08-04 Class II Terminated Z-2990-2020 Panther Fusion Tube Tray, Part: FAB-15004, REF: PRD-04000 Tube trays may leak which could invalidate patient results or assay worklists, causing delayed results for any assays with which they are used. A possibility ex…
2020-01-21 Class II Terminated Z-1343-2020 Selenia Dimensions Mammography System, Model number ASY-04160, Selenia Dimensions Gantry, UDI 15420045505636, The recalling firm has received reports from the field of the C-arm on the Selenia Dimensions system seizing or dropping during field repairs and cleaning of th…
Filings

All 510(k) clearances (25)

Date K-number Device Code Class Specialty
2026-08-12 K262792 Brevera Biopsy System with CorLumina Imaging Technology (BREVDISP09) KNW Class II Gastroenterology, Urology
2026-06-17 K253634 CoolSeal Generator® (CSL-200-90) GEI Class II General, Plastic Surgery
2025-09-25 K251993 Panther Fusion GI Expanded Bacterial Assay PCH Class II Microbiology
2025-09-25 K251868 Panther Fusion GI Bacterial Assay PCH Class II Microbiology
2025-07-31 K243341 Genius AI Detection 2.0 QDQ Class II Radiology
2025-02-13 K243396 Aptima SARS-CoV-2 Assay QQX Class II Microbiology
2025-01-17 K243935 Aptima CMV Quant Assay PAB Class II Microbiology
2024-11-25 K243345 Aptima BV Assay; Aptima CV/TV Assay PQA
2024-11-15 K242465 Panther Fusion SARS-CoV-2/Flu A/B/RSV assay QOF Class II Microbiology
2024-07-25 K240886 Fluent Pro Fluid Management System (FLT-200); Fluent Pro Fluid Management System Disposable Procedure Kit (6-pack) (FLT-212); Fluent Pro Fluid Management System Disposable Procedure Kit (1-pack) (FLT-212S); Fluent Pro Fluid Management System Tissue Trap Multipack (10-pack) (FLT-210); Fluent Pro Fluid Management System Waste Bag Multipack (5-pack) (FLT-205) HIG Class II Obstetrics/Gynecology
2024-07-24 K233352 Aptima HCV Quant Dx Assay MZP
2024-07-18 K241240 Panther Fusion SARS-CoV-2/Flu A/B/RSV Assay QOF Class II Microbiology
2024-01-31 DEN210035 “Genius™ Digital Diagnostics System with the Genius™ Cervical AI algorithm” QYV
2024-01-26 K231329 Aptima Neisseria gonorrhoeae Assay LSL
2023-11-16 K230451 Aptima® Chlamydia trachomatis Assay MKZ Class I Microbiology
2023-11-06 K231316 Aptima Trichomonas vaginalis Assay OUY Class II Immunology
2023-05-23 K230096 Genius AI Detection 2.0 with CC-MLO Correlation QDQ Class II Radiology
2023-05-16 K222736 Panther Fusion SARS-CoV-2/Flu A/B/RSV Assay QOF Class II Microbiology
2023-05-05 K231017 Panther Fusion AdV/hMPV/RV Assay OCC Class II Microbiology
2022-10-06 K221449 Genius AI Detection 2.0 QDQ Class II Radiology
2022-06-03 K220321 Aptima Combo 2 Assay (250 test kit) Panther, Aptima Combo 2 Assay (250 test kit) Tigris, Aptima Trichomonas Vaginalis Assay (250 test kit) Panther, Aptima Trichomonas Vaginalis Assay (250 test kit) Tigris QEP
2020-11-18 K201019 Genius AI Detection QDQ Class II Radiology
2020-10-05 K202294 Affirm Contrast Biopsy IZH Class II Radiology
2020-05-17 K200866 Aptima Combo 2 Assay (Panther System), Aptima Combo 2 Assay (Tigris) System) QEP
2020-03-23 K200436 Aptima Combo 2 Assay (Panther) - 250 test kit, Aptima Combo 2 Assay (Tigris) - 250 test kit, Aptima Trichomonas Vaginalis (Panther) - 250 test kit, Aptima Trichomonas Vaginalis (Tigris) - 250 test kit QEP